Probably the most popular medical work of the fifteenth century, the Latin Regimen sanitatis [Rule of Health] was translated into almost every European language following its first appearance in print in 1480. Nearly forty different editions were produced before 1501. Composed in the twelfth or thirteenth century, the Regimen is a didactic poem of domestic medical practice, containing commonsense rules and advice on diet for the maintenance of good health. Excerpt from Regimen sanitatis (Venice, 1500) with doodles in the margin showing a rabbit and a boar, as well as marginal notes and underlining of the text
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