Although the use of extracts from the foxglove in cases of dropsy had been common, William Withering was the first to analyze preparations of the plant scientifically and so isolated digitalis. Withering's An account of the foxglove describes over 150 cases in which he administered digitalis and established safe dosages for use. Fold-out insert of an etching of the foxglove plant, digitalis purpurea, from William Withering's An account of the foxglove, and some of its medical uses
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