After receiving his medical degree from Harvard, Holmes was granted the Boylston Prize in 1836 for his essay responding to the question “How far are the external means of exploring the condition of internal organs to be considered useful and important in medical practice?”The essay makes frequent reference to the lectures and clinical demonstrations of P. C. A. Louis which Holmes had recently attended in Paris. This copy was presented by Holmes to his mentor, Dr. James Jackson (1777-1867). Holmes was also awarded two Boylston Prizes in 1837 for separate essays on neuralgia and intermittent fever in New England. Cover page of the bound copy of the winning dissertations of the Boylston Prize in 1836, called Dissertations on the question “How far are the external means of exploring the condition of internal organs to be considered useful and important in medical practice?”
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