Jerome Wiesner was a Science Advisor to Presidents Eisenhower, Kennedy, and Johnson, and an arms control advocate. In the interview he discusses the nuclear arms race. He explains his ideal nuclear strategy, which involves a minimal deterrent, or a hundred bombs on a hundred cities, which should be adequate as long as the missiles are protected and precise, and which would greatly limit the number of nuclear weapons in the world. He also explains other nuclear strategies, including first strike, counterforce, and mutual assured destruction. He argues that the development of more precise systems has been destabilizing, and he provides reasons why he grew discouraged over the prospects for missile defense. He goes on to defend his arguments against an anti-ballistic missile (ABM) defense, an expansive civil defense program, and the B-70 bomber.